Data Engineer/Senior Data Engineer/Lead Data Engineer

Remote

Full Time

Experienced

Job Title: Data Engineer/Senior Data Engineer/Lead Data Engineer

Location: San Diego, San Mateo, Remote
FLSA Status: Exempt
ClearNote Health is a precision oncology company developing non-invasive diagnostic tests that detect cancer early—when it’s most treatable. We are seeking a Lead Data Engineer to play a pivotal role in shaping and operating the data infrastructure that powers both our scientific discovery and commercial execution.

In this high-impact role, you’ll be responsible for architecting and maintaining the data systems that unify our business, clinical, and scientific data into a trusted and accessible platform. You’ll collaborate cross-functionally with R&D, Lab Operations, G&A, Regulatory, and Software Engineering teams to ensure timely, accurate, and secure access to critical data.

This is an outstanding opportunity for an experienced data engineer who thrives in a fast-paced environment, enjoys working across diverse domains, and is passionate about using data to transform patient outcomes.

Key Responsibilities

Partner with stakeholders across the company to understand their data needs and the systems generating that data.
Design and implement a scalable, sustainable and reliable data operations strategy.
Own the architecture and ongoing evolution of our enterprise data warehouse.
Develop and maintain data contracts between systems of record and the warehouse to ensure data quality and transparency.
Continuously improve the architecture and pipelines for ingesting, transforming, and delivering data.
Create and maintain high-quality documentation for systems, pipelines, and data models.
Collaborate with QA and Regulatory teams to ensure data systems support clinical and regulatory requirements.
Work closely with the R&D team to capture, organize and analyze NGS-based laboratory data from R&D and production environments.
Collaborate with BI team to deliver data from scientific analysis to our business intelligence platform.

Qualifications

Bachelor's degree in Computer Science, Information Systems, Laboratory Science, or a related field; Master’s degree preferred.
3+ years of experience in data engineering or data operations roles.
Strong proficiency in SQL and Python.
Demonstrated experience with data warehousing and transforming raw data into useful models for business and scientific use.
Excellent written and verbal communication skills, with the ability to collaborate effectively across technical and non-technical teams.
Experience working with scientific data, particularly from next-generation sequencing (NGS), is strongly preferred.
Familiarity with common bioinformatics data formats is a plus.
Bonus: Familiarity with laboratory workflows and relevant regulatory standards (e.g., FDA, CLIA, ISO).

What We Value

At ClearNote Health, we are driven by our mission and guided by our values:
- Put Patients First
- Redefining the Possible
- Together We Win

Compensation

Title and compensation will be commensurate with skills, experience, and qualifications. The estimated base salary range for this position is $140,000 to $250,000, with potential variation based on depth of experience and location. This role includes stock options and generous benefits.

Come join us in addressing large healthcare needs through precision epigenomic medicine!

ClearNote Health is an exciting life science company that is reinventing non-invasive molecular diagnostic testing using next generation epigenomic technologies. We are passionate and dedicated to discovering and developing medicines that will make a significant difference in cancer and other epigenomic-driven diseases. Our technologies provide novel insight and quantitation of human health and disease, with our focus on precision medicine applications improving both clinical and health system outcomes. Our company was founded based on pioneering work in the Stanford laboratory of Stephen Quake, with advisors from Stanford and UCSF.

We look for extraordinary lifelong learners with a passion and growth mindset for these areas, and for combining biological ingenuity with AI and data analysis. Led by a team with decades of experience bringing products from concept to market, we are an equal opportunity employer and value diversity at our company.

We provide generous benefits to all employees including stock options. We are building a world-class company, based in San Diego and San Mateo.

Our commitment to Diversity, Equity, Inclusion, and Belonging:

We celebrate diversity in perspectives and backgrounds, and this is reflected in our innovation, our mission, and values. Our differences make us unique, help us innovate, and allow us to persevere. We strive to achieve representation and inclusion and redefine the possible in patients living longer lives.

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Come join us in early detection of cancer leading to improved outcomes and survival, resulting in healthier lives.

ClearNote Health is building a world-class team focused on our unique epigenomic platform to make long-term cancer survival a reality for more people. Together, we aim to help identify people with cancer earlier to enhance their treatment options for them to live longer, healthier lives.